Q: The doctor pointed out that the lymphopenia was indicative of a poor prognosis. Did they see further decrease in the lymphocyte count as the disease progressed?

Answer:

Yes, severe or critically ill COVID-19 patients showed that Lymphopenia is positively related with poor prognosis. If the treatment is not working for the patients.  The lymphocyte count will not increase and sometimes decrease when the condition of patients goes rapid deterioration and even death.

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet, undefined(undefined), undefined. doi:10.1016/S0140-6736(20)30566-3


Q: Is there a resource with a protocol for directing care from suspected COVID-19 patients, so that they are triaged into appropriate care? (eg. Not infected, infected outpatient quarantine, inpatient observation, critical

Answer:

People suspected of being infected by COVID-19 should accept virus test ASAP. If the test result is positive, they should be immediately quarantined or admitted to the hospital for treatment. If the test result is negative (at least twice repeatedly), they will can go home for isolation. If the virus tests of the patient are negative (at least twice repeatedly) after the treatment, they will be discharged from the hospital to the isolation point for medical observation for another two weeks, then go back home if there are no recurrence of symptoms.

Q: Why the need to do CRP if lymphopenia is sign of poor prognosis? CRP is non-specific for inflammation.

Answer:

In general, COVID-19 patients always had concomitant bacterial infection and sometimes systemic inflammatory storm. CRP could be a measurement for the evaluation of treatment.

Q: How is your criteria for use of isolation and ICU bed? And distribute limited materials.

Answer:

 You know, early diagnosis, treatment and isolation should be carried out whenever possible. Suspected cases and confirmed cases should be treated in isolation with protective conditions. Suspected cases should be treated in a single room, and confirmed cases can be admitted to the same ward. Confirmed cases include mild cases, moderate cases, severe cases and critical cases, the critical cases should be treated in ICU as soon as possible.

Q: Do you have any dynamic risk scores for COVID-19 patients?

Answer:

We don’t have detailed dynamic risk scores for COVID-19 patients. A confirmed case is based on epidemiological history (including cluster transmission), clinical manifestations (fever and respiratory symptoms), lung imaging, and results of COVID-19 nucleic acid detection and serum-specific antibodies. We use clinical classifications to determine the degree of risk for patients. Confirmed cases include mild cases, moderate cases, severe cases and critical cases, critical cases are further divided into early, middle and late stages according to the oxygenation index and compliance of respiratory system.